Preliminary Program

Scientific Program

The final meeting agenda can be downloaded here. 

The Metastatic Niche: Models, Mechanisms and Translating Targets into Therapeutics

 

8:00 a.m. Registration
Session 1: The Pre-Metastatic Niche
Moderator: Rosandra Kaplan, MD, National Cancer Institute
8:50 a.m. Rosandra Kaplan, M.D., National Cancer Institute
9:15 a.m. David Lyden, Ph.D., Memorial Sloan Kettering Cancer Center
"Tumor Exosomes Determine Organ-Specifc Metastasis"
10:05 a.m. Li Yang, Ph.D., National Cancer Institute
"Myeloid TGF-β Signaling, Inflammation and Cancer Metastases"
10:40 a.m. Sachie Hiratsuka, Ph.D., Tokyo Women's Medical University
"Formation and Regulation of Pre-Metastatic Niche"
11:15 a.m. Selected Abstract Speakers -
Ishan Barman, Ph.D., Johns Hopkins University
Meera Murgai, Ph.D., National Cancer Institute
11:45 a.m. Lunch
Session 2: EMT/Stem Cells
Moderator: Janine Erler, Ph.D., BRIC Biotech Research & Innovation Centre
12:45 p.m. Ilaria Malanchi, Ph.D., The Francis Crick Institute
"The Social Nature of Cancer Cells: How Well Do We Know Their Neighbours?"
1:20 p.m. Ken Pienta, M.D., Johns Hopkins University
"Transmogrifcation: Another Way to Look at EMT!"
1:55 p.m. Sohail Tavazoie, Ph.D., Rockefeller University
"Small-RNAs as Molecular Probes into the Biology and Therapy of Metastatic Disease"
2:30 p.m. Selected Abstract Speaker -
Sandra McAllister, Ph.D., Brigham & Women's Hospital, Harvard Medical School
2:45 p.m. Break
Session 3: Models of Metastatasis that Include the Microenviroment/Intact Immune System
Moderator: Lalage Wakefeld, D.Phil., National Cancer Institute
3:00 p.m. Valerie Weaver, Ph.D., University of California, San Francisco
"Forcing Tumor Aggression and Metastasis"
3:35 p.m. Cyrus Ghajar, Ph.D., Fred Hutchinson Cancer Research Center
"The Perivascular Niche Protects Dormant Disseminated Tumor Cells from Therapy"
4:10 p.m. Zena Werb, Ph.D., University of California, San Francisco
"Myeloid Cell Skewing in Response to Tumors"
4:45 p.m. Selected Abstract Speaker -
Alejandro Mayorca-Guilian, Ph.Di, University of Copenhagen
5:00 p.m. Break
Breakout Disusssion Sessions
5:15 p.m. Communication Between Primary Tumor to Metastatic Sites/Systemic Nature of Cancer
Moderators: Lalage Wakefeld, D.Phil., National Cancer Institute, Zena Werb, Ph.D., University of California, San Francisco and Janine Erler, Ph.D., BRIC Biotech Research & Innovation Centre
5:45 p.m. Bringing the Science into the Clinic
Moderators: Patricia Steeg, Ph.D., National Cancer Institute, Robert Kerbel, Ph.D., University of Toronto, Bruce Zetter, Ph.D., Boston Children's Hospital and Rosandra Kaplan, M.D., National Cancer Institute
6:30 p.m. Poster Session, Building 60, The Cloisters