The Metastatic Niche: Models, Mechanisms and Translating Targets into Therapeutics
|Moderator: Rosandra Kaplan, MD, National Cancer Institute|
|8:50 a.m.||Rosandra Kaplan, M.D., National Cancer Institute|
|9:15 a.m.||David Lyden, Ph.D., Memorial Sloan Kettering Cancer Center
"Tumor Exosomes Determine Organ-Specifc Metastasis"
|10:05 a.m.||Li Yang, Ph.D., National Cancer Institute
"Myeloid TGF-β Signaling, Inflammation and Cancer Metastases"
|10:40 a.m.||Sachie Hiratsuka, Ph.D., Tokyo Women's Medical University
"Formation and Regulation of Pre-Metastatic Niche"
|11:15 a.m.||Selected Abstract Speakers -
Ishan Barman, Ph.D., Johns Hopkins University
Meera Murgai, Ph.D., National Cancer Institute
|Moderator: Janine Erler, Ph.D., BRIC Biotech Research & Innovation Centre|
|12:45 p.m.||Ilaria Malanchi, Ph.D., The Francis Crick Institute
"The Social Nature of Cancer Cells: How Well Do We Know Their Neighbours?"
|1:20 p.m.||Ken Pienta, M.D., Johns Hopkins University
"Transmogrifcation: Another Way to Look at EMT!"
|1:55 p.m.||Sohail Tavazoie, Ph.D., Rockefeller University
"Small-RNAs as Molecular Probes into the Biology and Therapy of Metastatic Disease"
|2:30 p.m.||Selected Abstract Speaker -
Sandra McAllister, Ph.D., Brigham & Women's Hospital, Harvard Medical School
|Moderator: Lalage Wakefeld, D.Phil., National Cancer Institute|
|3:00 p.m.||Valerie Weaver, Ph.D., University of California, San Francisco
"Forcing Tumor Aggression and Metastasis"
|3:35 p.m.||Cyrus Ghajar, Ph.D., Fred Hutchinson Cancer Research Center
"The Perivascular Niche Protects Dormant Disseminated Tumor Cells from Therapy"
|4:10 p.m.||Zena Werb, Ph.D., University of California, San Francisco
"Myeloid Cell Skewing in Response to Tumors"
|4:45 p.m.||Selected Abstract Speaker -
Alejandro Mayorca-Guilian, Ph.Di, University of Copenhagen
|5:15 p.m.||Communication Between Primary Tumor to Metastatic Sites/Systemic Nature of Cancer
Moderators: Lalage Wakefeld, D.Phil., National Cancer Institute, Zena Werb, Ph.D., University of California, San Francisco and Janine Erler, Ph.D., BRIC Biotech Research & Innovation Centre
|5:45 p.m.||Bringing the Science into the Clinic
Moderators: Patricia Steeg, Ph.D., National Cancer Institute, Robert Kerbel, Ph.D., University of Toronto, Bruce Zetter, Ph.D., Boston Children's Hospital and Rosandra Kaplan, M.D., National Cancer Institute
|6:30 p.m.||Poster Session, Building 60, The Cloisters|