THE METASTATIC NICHE: Models, Mechanisms and Translating Targets

THE METASTATIC NICHE:

Models, Mechanisms and Translating Targets

A one-day symposium hosted by the National Cancer Institute

March 31, 2017 - Bethesda, MD

Metastasis remains the most challenging aspect of cancer biology. Metastatic outcome is dictated by both cell intrinsic and cell extrinsic signals that determine metastatic tumor cell survival and growth. A conducive microenvironment in distant tissue sites is composed of hematopoietic and stromal cells as well as extracellular matrix. This dynamic environment can support disseminated tumor cells, similar to a stem cell niche.

This symposium brings together world-leading researchers in the field of metastasis, stem cells, tumor microenvironment and cancer progression in the vibrant setting of Bethesda, MD steps from the nation’s capital. The meeting is just prior to the AACR Annual Meeting being held in Washington, DC.